Reducing hotel employee turnover intention by promoting pride in job and meaning of work: A cross-cultural perspective

Characterizing with an image of low-skilled jobs and low social status, the hotel industry is undergoing a "great resignation" from staff due to stress post-Covid-19, urging a need to encourage hotel employees to stay with their jobs. This study attempted to explore whether employees' turnover intention was decreased by promoting their pride in jobs and how job pride was predicted by dimensions of the meaning of work. Two online surveys were conducted on American and Vietnamese hotel employees. A structural equation modeling analysis revealed that work centrality, obligation norms, and work values positively affected job pride which subsequently reduced turnover intention. The study also showed the negative relationship between job pride and turnover intention was only significant for Americans, confirming the culture's moderation role. The findings provide valuable theoretical contributions regarding employees' behavioral intention from a multicultural perspective and managerial implications for hoteliers in human resources management practices.

Outcome Study Among Hospitalized Symptomatic COVID-19 Patients Who Required Chronic vs. Acute Hemodialysis (HD)

Background: Mortality among patients admitted for COVID19 infections who develop acute kidney injury (AKI) and require dialysis support has been reported to be >=60-70%. Data are lacking regarding how chronic HD patients with an impaired immune system may: 1) mount an inflammatory response to COVID19 infection and 2) survive the infection compared with those who require acute HD for AKI. We evaluated ferritin levels, hospital length of stay (LOS), and mortality rates among chronic HD patients and those who required acute HD during hospitalization for COVID19-related symptoms. Method(s): Inclusion: All patients hospitalized for COVID19-related symptoms who received HD at OV-UCLA Medical Center from January to December 2020. Data collection: Baseline characteristics: age, gender, body mass index (BMI), comorbidities (diabetes mellitus, hypertension, underlying chronic obstructive lung disease or asthma, history of malignancy, and heart failure). Medications: use of any inhibitor of the renin angiotensin aldosterone system. Lab studies: albumin, ferritin, basic chemistry. Hospital LOS and death from any cause. Data analysis: Ferritin levels, hospital LOS, and mortality among chronic and acute HD patients. Result(s): See Figure Conclusion(s): Among our hospitalized symptomatic COVID19 patients requiring HD support: 1. Ferritin levels were comparable between chronic HD and previously nondialysis patients who required acute HD support. 2. Chronic HD patients had shorter hospital LOS compared with those requiring acute HD (6.2 +/- 5.7d vs. 35.3 +/- 31.3d). The 2 groups had similar serum sodium, albumin, and ferritin levels. 3. Mortality was <5% (compared with 1.5% for the US population).among chronic HD patients and 58% among those who developed AKI requring acute HD. 4. Incidentally, BMI among current COVID19 cohort was 30.6 +/- 8.8 compared with 26.4 +/- 5.8 Kg/m2 from our 70 non- COVID dialysis patients included in a different study (p-value <0.001). (Figure Presented).

Crescentic IgA Nephropathy (cIgAN) in a Patient With COVID-19 Infection

Introduction: COVID19 infection has been linked to various glomerulonephropathies (GN) including collapsing focal segmental glomerulosclerosis, pauciimmune crescentic glomerulonephritis, and possibly minimal change disease and IgA nephropathy. Case Description: A 57-year-old obese man with hypertension, hyperlipidemia, prediabetes, chronic obstructive pulmonary disease, illicit drug use, status post Pfizer COVID vaccine (1st dose 4m prior, 2nd dose 3w later), and COVID19 infection 7w prior, presented with an acute onset purpuric rash that began from bilateral hands and feet and progressed to arms and legs. Patient denied joint pain or abdominal discomfort. Initial studies: Serum creatinine (Cr) 4.17 mg/dL (2.37 mg/dL 2w prior, baseline 0.93 mg/dL 4m prior). Urinalysis: > 50 red blood cells/high power field;Urine protein/Cr 4g/g, albumin/Cr >3g/g;Negative: HIV, ANCA, ANA, antiGBM, complements. Chest CT: Bilateral multifocal consolidative opacities concerning for aspiration, multifocal bacterial or viral pneumonia, or atypical presentation of COVID19 pneumonia. Skin biopsy: Leukocytoclastic vasculitis;No immunoreactants detected. Patient suffered from rapid respiratory deterioration, multiple hypotensive episodes, and acute kidney injury requiring mechanical ventilation and dialysis support. Kidney biopsy: IgA dominant immune complex mediated glomerulonephritis with focal/remote fibrous crescents;acute tubular injury. Treatment: Intravenous methylprednisolone 250 mg x 3d, followed by oral prednisone course. Patient recovered adequate function after 6w and was able to discontinue dialysis. Discussion(s): COVID19 infection-related inflammatory response may precipitate GN in susceptible individuals. Crescentic IgAN is known to be associated with acute inflammatory conditions involving lungs, gastrointestinal tract, and skin. The timeline for the development of cIgAN herein raises suspicion for COVID19 infection/pneumonia as the inciting event. (Figure Presented).

Subclinical Kidney Allograft Rejection Without Maintenance Immunosuppressive Therapy (mIST)

Introduction: Kidney transplant (KTx) generally requires mIST to prevent rejection and graft loss. A mother-to-son kidney recipient presents with preserved kidney function despite being off mIST for 26 years. Case Description: A 44-year-old man with diabetes mellitus, unknown congenital kidney disease requiring peritoneal dialysis for 3y and KTx from his mother at age 13, and status post COVID19 infection 2m prior, presents with diabetic ketoacidosis due to insulin nonadherence. Patient received unknown mIST until age 18 when he self-discontinued therapy. Initial studies: Serum: glucose1064 mg/dL, pH 7.28, +ketones, creatinine (Cr) 2.4 mg/dL (baseline Cr 1.1);Urinalysis 4-10 white blood cells/high power field, few bacteria;Urine protein/Cr 0.4 g/g, albumin/Cr 0.1 g/g Patient received insulin and fluid with Cr improved to 1.1 mg/dL. Fig 1 shows Cr timeline. Kidney biopsy was performed prior to discharge to determine the need for mIST reinitiation. While awaiting for pathology report as outpatient, Cr increased to 1.82 mg/dL. Pathology Fig 2: Chronic active T-cell-mediated tubulointerstitial rejection, active vascular rejection, and chronic active antibody-mediated rejection. Patient was readmitted for intravenous immunoglobulin & antithymocyte globulin with appropriate Cr improvement and discharged on prednisone, mycophenolate, & tacrolimus. Donor HLA-typing was not available for donor specificic antibody testing. Discussion(s): The case demonstrates 1) Subclinical rejection may occur in the setting of prolonged IST discontinuation and 2) Cr is insensitive in detecting rejection and raises the possibility of COVID19-induced exacerbation of ongoing low-level rejection. (Figure Presented).

Factors Affecting Income from Public Agricultural Land Use: An Empirical Study from Vietnam

The study aims to determine the factors and their influence on the income from using public agricultural land of households. Public agricultural land is agricultural land, including land for growing annual crops, perennial crops, and land for aquaculture, leased by commune-level People's Committees with a lease term of not more than 5 years. Secondary data were collected for the 2017-2021 period at state agencies. Primary data were collected from a survey of 150 households renting public agricultural land. The regression model assumed that there were 28 factors belonging to 7 groups. The test results show that 25 factors affect income, and 03 factors do not. The group of COVID-19 pandemic factors has the strongest impact, followed by the groups of agricultural product market factors, land factors, capital factors, production cost factors, labor factors, and climatic factors. The impact rate of COVID-19 pandemic factors is the largest (23.00%);The impact rate of climatic factors is the smallest (6.04%). Proposals to increase income include good implementation of disease prevention and control;increasing the land lease term;accurately forecasting the supply and demand of the agricultural market;raising the level of the household head;ensuring sufficient production capital, and adapting to the climate.

Post-COVID-19 pulmonary fibrosis: the rationale of mesenchymal stem cell transplantation for lung regeneration

Coronavirus disease 2019 (COVID-19) has caused nearly 15 million deaths worldwide. The rapid development of COVID-19 vaccines and anti-viral drugs significantly decreased the level of mortality related to COVID-19. However, post-COVID-19 pulmonary fibrosis has become a severe problem for some COVID-19 patients. The previous articles present the results of mesenchymal stem cell (MSC) transplantation to treat COVID-19 patients;in this article, we would like to discuss the potential of MSC transplantation to treat and improve post- COVID-19 pulmonary fibrosis. MSCs exhibit immune modulation and anti-inflammation that can control the inflammation caused by coronavirus 2 infection and the cytokine storm that some patients experience during COVID-19. The anti-fibrotic qualities of MSCs have also been demonstrated both in vitro and in vivo. Based on the current information about the anti-fibrotic effects of MSCs, MSC transplantation can be used to improve post-COVID-19 pulmonary fibrosis.

Higher SARS-CoV-2 RT-PCR cycle threshold (CT) values associated with longer symptom duration among patients hospitalized with COVID-19

Background: Most diagnostic tests for SARS-CoV-2, the causative agent of COVID-19, are RT-PCR based. This method is sensitive but cannot distinguish replicating from non-replicating virus. RT-PCR cycle threshold (Ct) values are inversely correlated with viral load, and higher Ct values have been correlated with lower in vitro viral infectivity. However, relatively few data exist on the association between Ct values and patients' duration of symptoms remains unclear. We thus evaluated Ct values and symptom duration in a cohort of patients hospitalized with COVID-19. Methods: We assessed all patients admitted to San Francisco General Hospital between April 1 and May 18, 2020 with confirmed COVID-19 infection based on RT-PCR testing (Abbott m2000 platform). We included patients having diagnostic testing for suspected COVID-19 and patients having asymptomatic testing per hospital policy. For symptomatic patients, date of symptom onset was abstracted from hospital records, and time from symptom onset to test date was calculated. RT-PCR Ct values were manually extracted. Median Ct and IQR were calculated for patients with < 10 days of symptoms, ≥10 days of symptoms, and asymptomatic disease. Betweengroup comparisons were performed using the Kruskal-Wallis test. Results: Among 61 patients with positive RT-PCR tests, 40 patients reported < 10 days of symptoms at the time of testing, 15 reported ≥10 days of symptoms, and 6 were asymptomatic. The median Ct value was 14.2 cycles (IQR, 10.2, 18.3) among patients reporting < 10 days of symptoms, 19.7 cycles (IQR, 15.3, 23.9) among patients reporting ≥10 days of symptoms, and 26.3 (IQR, 25.0, 29.1) among asymptomatic patients. Ct values were significantly lower among patients with < 10 days of symptoms compared to patients with >=10 days of symptoms (p=0.01) and when compared to asymptomatic patients (p=0.0002) [Figure]. Conclusion: SARS-CoV-2 RT-PCR cycle threshold values were higher (indicating lower viral load) in patients with longer symptom duration and were highest in asymptomatic patients. These results add to emerging data suggesting that strategies for optimal isolation of patients in both community and hospital settings could be informed by a combination of symptom duration and RT-PCR Ct values. (Table Presented).